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1

Loss of viability during freeze–thaw of intact and adherent human embryonic stem cells with conventional slow-cooling protocols is predominantly due to␣apoptosis rather than cellular necrosis

Boon Chin Heng, Chao Peng Ye, Hua Liu, Wei Seong Toh, Abdul Jalil Rufaihah, Zheng Yang, Boon Huat Bay, Zigang Ge, Hong Wei Ouyang, Eng Hin Lee, Tong Cao

Journal:

Journal of Biomedical Science

Year:

2006

Language:

english

File:

PDF, 665 KB

english, 2006

2

Modulation of chondrocyte functions and stiffness-dependent cartilage repair using an injectable enzymatically crosslinked hydrogel with tunable mechanical properties

Wang, Li-Shan, Du, Chan, Toh, Wei Seong, Wan, Andrew C.A., Gao, Shu Jun, Kurisawa, Motoichi

Journal:

Year:

2014

Language:

english

File:

PDF, 3.40 MB

english, 2014

3

Adipose Tissue and Extracellular Matrix Development by Injectable Decellularized Adipose Matrix Loaded with Basic Fibroblast Growth Factor

Zhang, Shipin, Lu, Qiqi, Cao, Tong, Toh, Wei Seong

Journal:

Plastic & Reconstructive Surgery

Year:

2016

Language:

english

File:

PDF, 3.15 MB

english, 2016

4

MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis

Zhang, Shipin, Teo, Kristeen Ye Wen, Chuah, Shang Jiunn, Lai, Ruenn Chai, Lim, Sai Kiang, Toh, Wei Seong

Journal:

Year:

2019

Language:

english

File:

PDF, 3.13 MB

english, 2019

5

Mesenchymal stem cell exosomes enhance periodontal ligament cell functions and promote periodontal regeneration

Chew, Jacob Ren Jie, Chuah, Shang Jiunn, Teo, Kristeen Ye Wen, Zhang, Shipin, Lai, Ruenn Chai, Fu, Jia Hui, Lim, Lum Peng, Lim, Sai Kiang, Toh, Wei Seong

Journal:

Acta Biomaterialia

Year:

2019

File:

PDF, 1.71 MB

2019

6

Mesenchymal Stem Cell Exosomes in Bone Regenerative Strategies â A Systematic Review of Preclinical Studies

Tan, Si Heng Sharon, Wong, Joshua Rui Yen, Sim, Sharmaine Jia Ying, Tjio, Calvin Kai En, Wong, Keng Lin, Chew, Jacob Ren Jie, Hui, James Hoi Po, Toh, Wei Seong

Journal:

Materials Today Bio

Year:

2020

File:

PDF, 4.13 MB

2020

7

Culture media conditioned by heat-shocked osteoblasts enhances the osteogenesis of bone marrow-derived mesenchymal stromal cells

Chao Peng Ye, Boon Chin Heng, Hua Liu, Wei Seong Toh, Tong Cao

Journal:

Cell Biochemistry and Function

Year:

2007

Language:

english

File:

PDF, 293 KB

english, 2007

8

Directing endothelial differentiation of human embryonic stem cells via transduction with an adenoviral vector expressing the VEGF165 gene

Abdul Jalil Rufaihah, Husnain Khawaja Haider, Boon Chin Heng, Lei Ye, Wei Seong Toh, Xian Feng Tian, Kai Lu, Eugene Kwang-Wei Sim, Tong Cao

Journal:

The Journal of Gene Medicine

Year:

2007

Language:

english

File:

PDF, 5.31 MB

english, 2007

9

Cartilage repair using hyaluronan hydrogel-encapsulated human embryonic stem cell-derived chondrogenic cells

Wei Seong Toh, Eng Hin Lee, Xi-Min Guo, Jerry K.Y. Chan, Chen Hua Yeow, Andre B. Choo, Tong Cao

Journal:

Year:

2010

Language:

english

File:

PDF, 3.66 MB

english, 2010

10

Molecular characterization of hepatitis B virus surface antigen mutants in Singapore patients with hepatocellular carcinoma and hepatitis B virus carriers negative for HBsAg but positive for anti-HBs and anti-HBc

*CHONG JIN OON, WEI NING CHEN, KEE TAI GOH, STEVEN MESENAS, HAN SEONG NG, GILBERT CHIANG, CLARENCE TAN, SHIUAN KOH, SIAW WEI TENG, IVY TOH, MEI CHUNG MOH, KIAN SIM GOO, KAELING TAN, AI LI

Journal:

Journal of Gastroenterology and Hepatology

Year:

2002

Language:

english

File:

PDF, 109 KB

english, 2002

11

Potential of Human Embryonic Stem Cells in Cartilage Tissue Engineering and Regenerative Medicine

Wei Seong Toh, Eng Hin Lee, Tong Cao

Journal:

Stem Cell Reviews and Reports

Year:

2011

Language:

english

File:

PDF, 298 KB

english, 2011

12

Human fibroblast matrices bio-assembled under macromolecular crowding support stable propagation of human embryonic stem cells

Yanxian Peng, Michael Thomas Bocker, Jennifer Holm, Wei Seong Toh, Christopher Stephen Hughes, Fahad Kidwai, Gilles Andre Lajoie, Tong Cao, Frank Lyko, Michael Raghunath

Journal:

Journal of Tissue Engineering and Regenerative Medicine

Year:

2012

Language:

english

File:

PDF, 927 KB

english, 2012

13

The effect of injectable gelatin-hydroxyphenylpropionic acid hydrogel matrices on the proliferation, migration, differentiation and oxidative stress resistance of adult neural stem cells

Teck Chuan Lim, Wei Seong Toh, Li-Shan Wang, Motoichi Kurisawa, Myron Spector

Journal:

Year:

2012

Language:

english

File:

PDF, 1.06 MB

english, 2012

14

Modulation of mesenchymal stem cell chondrogenesis in a tunable hyaluronic acid hydrogel microenvironment

Wei Seong Toh, Teck Chuan Lim, Motoichi Kurisawa, Myron Spector

Journal:

Year:

2012

Language:

english

File:

PDF, 1.64 MB

english, 2012

15

Differentiation and enrichment of expandable chondrogenic cells from human embryonic stem cells in vitro

Wei Seong Toh, Xi-Min Guo, Andre B. Choo, Kai Lu, Eng Hin Lee, Tong Cao

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 2.63 MB

english, 2009

16

A subpopulation of mesenchymal stromal cells with high osteogenic potential

Hua Liu, Wei Seong Toh, Kai Lu, Paul Anthony MacAry, David Michael Kemeny, Tong Cao

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 1.55 MB

english, 2009

17

Osteogenic differentiation within intact human embryoid bodies result in a marked increase in osteocalcin secretion after 12 days of in vitro culture, and formation of morphologically distinct nodule-like structures

Tong Cao, Boon Chin Heng, Chao Peng Ye, Hua Liu, Wei Seong Toh, Paul Robson, Pin Li, Yun Han Hong, Lawrence Walter Stanton

Journal:

Tissue and Cell

Year:

2005

Language:

english

File:

PDF, 719 KB

english, 2005

18

An autologous cell lysate extract from human embryonic stem cell (hESC) derived osteoblasts can enhance osteogenesis of hESC

Boon Chin Heng, Wei Seong Toh, Barry Peter Pereira, Bee Leng Tan, Xin Fu, Hua Liu, Kai Lu, Jin Fei Yeo, Tong Cao

Journal:

Tissue and Cell

Year:

2008

Language:

english

File:

PDF, 2.25 MB

english, 2008

19

Stage-Dependent Effect of TGF-β1 on Chondrogenic Differentiation of Human Embryonic Stem Cells

Yang, Zheng, Sui, Lin, Toh, Wei Seong, Lee, Eng Hin, Cao, Tong

Journal:

Stem Cells and Development

Year:

2009

Language:

english

File:

PDF, 496 KB

english, 2009

20

Differentiation of Human Embryonic Stem Cells into Clinically Amenable Keratinocytes in an Autogenic Environment

Kidwai, Fahad K, Liu, Hua, Toh, Wei Seong, Fu, Xin, Jokhun, Doorgesh S, Movahednia, Mohammad M, Li, Mingming, Zou, Yu, Squier, Christopher A, Phan, Toan T, Cao, Tong

Journal:

The Journal of Investigative Dermatology

Year:

2013

Language:

english

File:

PDF, 2.80 MB

english, 2013

21

Effects of Culture Conditions and Bone Morphogenetic Protein 2 on Extent of Chondrogenesis from Human Embryonic Stem Cells

Wei Seong Toh, Zheng Yang, Hua Liu, Boon Chin Heng, Eng Hin Lee, Tong Cao

Journal:

Year:

2007

Language:

english

File:

PDF, 777 KB

english, 2007

22

Advances in hydrogel delivery systems for tissue regeneration

Toh, Wei Seong, Loh, Xian Jun

Journal:

Materials Science and Engineering: C

Year:

2014

Language:

english

File:

PDF, 866 KB

english, 2014

23

Predictive human kidney-specific in vitro models

Li, Yao, Oo, Zay Yar, Toh, Wei Seong, Zink, Daniele

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 71 KB

english, 2013

24

Advances in Mesenchymal Stem Cell-based Strategies for Cartilage Repair and Regeneration

Toh, Wei Seong, Foldager, Casper Bindzus, Pei, Ming, Hui, James Hoi Po

Journal:

Stem Cell Reviews and Reports

Year:

2014

Language:

english

File:

PDF, 433 KB

english, 2014

25

Identification of Nephrotoxic Compounds with Embryonic Stem-Cell-Derived Human Renal Proximal Tubular-Like Cells

Li, Yao, Kandasamy, Karthikeyan, Chuah, Jacqueline Kai Chin, Lam, Yue Ning, Toh, Wei Seong, Oo, Zay Yar, Zink, Daniele

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 2.59 MB

english, 2014

26

Biomaterial-Mediated Delivery of Microenvironmental Cues for Repair and Regeneration of Articular Cartilage

Toh, Wei Seong, Spector, Myron, Lee, Eng Hin, Cao, Tong

Journal:

Molecular Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 3.72 MB

english, 2011

27

Combined effects of TGFβ1 and BMP2 in serum-free chondrogenic differentiation of mesenchymal stem cells induced hyaline-like cartilage formation

Toh, Wei Seong, Liu, Hua, Heng, Boon Chin, Rufaihah, Abdul Jalil, Ye, Chao Peng, Cao, Tong

Journal:

Year:

2005

Language:

english

File:

PDF, 1.02 MB

english, 2005

28

Basement membrane molecule expression attendant to chondrogenesis by nucleus pulposus cells and mesenchymal stem cells

Toh, Wei Seong, Foldager, Casper Bindzus, Olsen, Bjorn Reino, Spector, Myron

Journal:

Journal of Orthopaedic Research

Year:

2013

Language:

english

File:

PDF, 16.36 MB

english, 2013

29

Establishment of Clinically Compliant Human Embryonic Stem Cells in an Autologous Feeder-Free System

Fu, Xin, Toh, Wei Seong, Liu, Hua, Lu, Kai, Li, Mingming, Cao, Tong

Journal:

Tissue Engineering Part C Methods

Year:

2011

Language:

english

File:

PDF, 1.10 MB

english, 2011

30

Autologous Feeder Cells from Embryoid Body Outgrowth Support the Long-Term Growth of Human Embryonic Stem Cells More Effectively than Those from Direct Differentiation

Fu, Xin, Toh, Wei Seong, Liu, Hua, Lu, Kai, Li, Mingming, Hande, Manoor Prakash, Cao, Tong

Journal:

Tissue Engineering Part C Methods

Year:

2010

Language:

english

File:

PDF, 948 KB

english, 2010

31

Therapeutic angiogenesis by transplantation of human embryonic stem cell-derived CD133 + endothelial progenitor cells for cardiac repair

Rufaihah, Abdul Jalil, Haider, Husnain Khawaja, Heng, Boon Chin, Ye, Lei, Tan, Ru San, Toh, Wei Seong, Tian, Xian Feng, Sim, Eugene Kwang-Wei, Cao, Tong

Journal:

Regenerative Medicine

Year:

2010

Language:

english

File:

PDF, 3.86 MB

english, 2010

32

Investigation of Human Embryonic Stem Cell-Derived Keratinocytes as an In Vitro Research Model for Mechanical Stress Dynamic Response

Cherbuin, Thibaud, Movahednia, Mohammad Mehdi, Toh, Wei Seong, Cao, Tong

Journal:

Stem Cell Reviews and Reports

Year:

2015

Language:

english

File:

PDF, 6.14 MB

english, 2015

33

Differential Effects of the Extracellular Microenvironment on Human Embryonic Stem Cell Differentiation into Keratinocytes and Their Subsequent Replicative Life Span

Movahednia, Mohammad Mehdi, Kidwai, Fahad Karim, Zou, Yu, Tong, Huei Jinn, Liu, Xiaochen, Islam, Intekhab, Toh, Wei Seong, Raghunath, Michael, Cao, Tong

Journal:

Tissue Engineering Part A

Year:

2015

Language:

english

File:

PDF, 1.77 MB

english, 2015

34

Stem Cells for Temporomandibular Joint Repair and Regeneration

Zhang, Shipin, Yap, Adrian U. J., Toh, Wei Seong

Journal:

Stem Cell Reviews and Reports

Year:

2015

Language:

english

File:

PDF, 803 KB

english, 2015

35

Inducing pluripotency for disease modeling, drug development and craniofacial applications

Rosa, Vinicius, Toh, Wei Seong, Cao, Tong, Shim, Winston

Journal:

Expert Opinion on Biological Therapy

Year:

2014

Language:

english

File:

PDF, 524 KB

english, 2014

36

Potential applications of keratinocytes derived from human embryonic stem cells

Movahednia, Mohammad M., Kidwai, Fahad K., Jokhun, Doorgesh S., Squier, Christopher A., Toh, Wei Seong, Cao, Tong

Journal:

Biotechnology Journal

Year:

2016

Language:

english

File:

PDF, 1.78 MB

english, 2016

37

Cellular senescence in aging and osteoarthritis

Toh, Wei Seong, Brittberg, Mats, Farr, Jack, Foldager, Casper Bindzus, Gomoll, Andreas H, Hui, James Hoi Po, Richardson, James B, Roberts, Sally, Spector, Myron

Journal:

Acta Orthopaedica

Year:

2016

Language:

english

File:

PDF, 900 KB

english, 2016

38

Human mesenchymal stem cell-derived exosomes promote orderly cartilage regeneration in an immunocompetent rat osteochondral defect model

Zhang, Shipin, Wong, Keng Lin, Chu, Wern Cui, Lai, Ruenn Chai, Po Hui, James Hoi, Lee, Eng Hin, Lim, Sai Kiang, Toh, Wei Seong

Journal:

Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology

Year:

2016

Language:

english

File:

PDF, 45 KB

english, 2016

39

MSC exosome as a cell-free MSC therapy for cartilage regeneration: implications for osteoarthritis treatment

Toh, Wei Seong, Lai, Ruenn Chai, Po Hui, James Hoi, Lim, Sai Kiang

Journal:

Seminars in Cell & Developmental Biology

Year:

2016

Language:

english

File:

PDF, 550 KB

english, 2016

40

Depth of cure of contemporary bulk-fill resin-based composites

YAP, Adrian U Jin, PANDYA, Mirali, TOH, Wei Seong

Journal:

Dental Materials Journal

Year:

2016

Language:

english

File:

PDF, 840 KB

english, 2016

41

Distribution of pericellular matrix molecules in the temporomandibular joint and their chondroprotective effects against inflammation

Chu, Wern Cui, Zhang, Shipin, Sng, Timothy J, Ong, Yu Jie, Tan, Wen-Li, Ang, Vivien Y, Foldager, Casper B, Toh, Wei Seong

Journal:

International Journal of Oral Science

Year:

2017

Language:

english

File:

PDF, 4.58 MB

english, 2017

42

MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity

Zhang, Shipin, Chuah, Shang Jiunn, Lai, Ruenn Chai, Hui, James Hoi Po, Lim, Sai Kiang, Toh, Wei Seong

Journal:

Year:

2018

Language:

english

File:

PDF, 2.98 MB

english, 2018

43

Substrate stiffness modulates the multipotency of human neural crest derived ectomesenchymal stem cells via CD44 mediated PDGFR signaling

Srinivasan, Akshaya, Chang, Shu-Yung, Zhang, Shipin, Toh, Wei Seong, Toh, Yi-Chin

Journal:

Year:

2018

Language:

english

File:

PDF, 4.30 MB

english, 2018

44

Recent Progress in Stem Cell Chondrogenesis

Journal:

Progress in Stem Cell

Year:

2014

Language:

english

File:

PDF, 1.18 MB

english, 2014

45

Stem Cells: Microenvironment, Micro/Nanotechnology, and Application

Liu, Hua, Zhang, Zhiyong, Seong Toh, Wei, Ng, Kee Woei, Sant, Shilpa, Salgado, António

Journal:

Stem Cells International

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

46

Modulation of Dental Pulp Stem Cell Odontogenesis in a Tunable PEG-Fibrinogen Hydrogel System

Lu, Qiqi, Pandya, Mirali, Rufaihah, Abdul Jalil, Rosa, Vinicius, Tong, Huei Jinn, Seliktar, Dror, Toh, Wei Seong

Journal:

Stem Cells International

Year:

2015

Language:

english

File:

PDF, 3.43 MB

english, 2015

47

MSC exosome works through a protein-based mechanism of action

Toh, Wei Seong, Lai, Ruenn Chai, Zhang, Bin, Lim, Sai Kiang

Journal:

Biochemical Society Transactions

Year:

2018

Language:

english

File:

PDF, 687 KB

english, 2018

48

Which Source of Mesenchymal Stem Cell is Superior for Cartilage Regeneration of the Knee? A Systematic Review and Meta-Analysis

Chong, Jia Yan, See, Fabian Jun Ze, Wong, Keng Lin, Tan, Sharon Si Heng, Toh, Wei Seong, Hui, James Hoi Po

Journal:

Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology

Year:

2018

Language:

english

File:

PDF, 49 KB

english, 2018

49

Immune regulatory targets of mesenchymal stromal cell exosomes/small extracellular vesicles in tissue regeneration

TOH, WEI SEONG, ZHANG, BIN, LAI, RUENN CHAI, LIM, SAI KIANG

Journal:

Year:

2018

Language:

english

File:

PDF, 627 KB

english, 2018

50

New Perspectives in Chondrogenic Differentiation of Stem Cells for Cartilage Repair

Toh, Wei Seong, Yang, Zheng, Heng, Boon Chin, Cao, Tong

Journal:

The Scientific World JOURNAL

Year:

2006

Language:

english

File:

PDF, 1.12 MB

english, 2006

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